Ethical Principles for Medical Research

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The Declaration of Helsinki, the founding document of modern medical research ethics, provides a set of ethical principles regarding human experimentation.

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The World Medical Association’s Declaration of Helsinki provides principles for medical researchers to guide the ethical conduct of research involving human participants and specifically addresses protections for study participants with regard to the risks, burdens, and benefits of participating in studies as well as participants’ rights to privacy, confidentiality, and informed consent. The guidance also informs researchers about the proper conduct and reporting of research, including the use of study protocols, ethical approval of studies by research ethics committees (institutional review boards), study registration in public databases, publication/dissemination of study results, and guidance on use of placebo vs best proven intervention and unproven interventions.

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